Radiant energy – Ionic separation or analysis – Methods
Reexamination Certificate
2005-06-14
2005-06-14
Berman, Jack I. (Department: 2881)
Radiant energy
Ionic separation or analysis
Methods
C436S173000, C702S023000
Reexamination Certificate
active
06906320
ABSTRACT:
The present invention features mass spectrometry data analysis techniques that can be employed to selectively identify analytes differing in abundance between different sample sets. The employed techniques determine the statistical significance of changes to signals associated with mass-to-charge ratios (“m/z-intensity pairs”) between individual samples and sample sets. Based on the statistical significance, changes likely to indicate analyte level differences are identified. Based on intensities of the signals, ratios of analyte abundances can be determined.
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Caprion Pharmaceuticals, Inc., Pre
Sachs Jeffrey R.
Wiener Matthew C.
Yates Nathan A.
Berman Jack I.
Heber Sheldon O.
Merck & Co. , Inc.
Tribble Jack L.
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