Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2004-11-03
2009-11-03
Mondesi, Robert B (Department: 1645)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
Reexamination Certificate
active
07611856
ABSTRACT:
The present invention is directed to a method for detecting the presence of clostridial neurotoxins in a sample by mixing a sample with a peptide that can serve as a substrate for proteolytic activity of a clostridial neurotoxin; and measuring for proteolytic activity of a clostridial neurotoxin by a mass spectroscopy technique. In one embodiment, the peptide can have an affinity tag attached at two or more sites.
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Barr John R.
Boyer Anne E.
Kalb Suzanne R.
Moura Hercules
Schmidt Jurgen G.
Cottrell Bruce H.
Gangle Brian J
Jones Juliet A.
Los Alamos National Security LLC
Mondesi Robert B
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