Mass spectrometric analysis method and system using the method

Radiant energy – Ionic separation or analysis

Reexamination Certificate

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C250S282000, C250S286000, C250S288000, C250S398000

Reexamination Certificate

active

07435949

ABSTRACT:
A tandem analysis system is provided for ionizing a substance, performing mass spectrometric analysis of various ion types generated, selecting and dissociating an ion type, the ion type having a specific mass-to-charge ratio, and thereby, repeating mass spectrometric analysis measurement on the ion of the ion type over n-th stages. A processing judges control content for the analysis next to MSn(the n-th stage mass spectrometric analysis) within a predetermined time, based on ion intensity being represented by an ion peak with respect to the mass-to-charge ratio of each ion in the MSnresult. An ion detection unit judges isotope-peak from the measured ionized data. Assuming that the MS1count number of a parent-ion peptide measured during a certain constant time-interval is I, a data processing unit makes the MS2integration number-of-times or analysis time of the peptide proportional to 1/I.

REFERENCES:
patent: 3480774 (1969-11-01), Smith
patent: 5087815 (1992-02-01), Schultz et al.
patent: 7180056 (2007-02-01), Ohtake et al.
patent: 2001/0007349 (2001-07-01), Nagai
patent: 10-142196 (1998-05-01), None
patent: 2001-249114 (2001-09-01), None

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