Mass spectrometer system

Radiant energy – Ionic separation or analysis – With plural – simultaneous ion generators

Reexamination Certificate

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C250S288000, C250S281000

Reexamination Certificate

active

07026610

ABSTRACT:
There is provided an analyzer system capable of easily improving the efficiency of a charge reduction due to ion/ion reactions. A mass spectrometer system includes: a first ion source for ionizing a sample to be measured; a second ion source for producing ions of a polarity reversed from that of the ions produced in said first ion source; an ion deflector for introducing and deflecting the ions of said first and second ion sources; an ion-trap mass spectrometer including a ring electrode and a pair of endcap electrodes; and a detector for detecting the ions ejected from the mass spectrometer, wherein the ions from said first and second ion sources are introduced together through the ion deflector into the ion-trap mass spectrometer; the ions from the two ion sources are mixed in the ion-trap mass spectrometer; and in that the ions are then detected in the detector. Reactant ions can be sufficiently supplied to improve the efficiency of the charge reduction due to the ion/ion reactions

REFERENCES:
patent: 6469297 (2002-10-01), Kato
patent: 6541768 (2003-04-01), Andrien et al.
patent: 6583409 (2003-06-01), Kato
patent: 6596989 (2003-07-01), Kato
patent: 2002/0036263 (2002-03-01), Shiokawa et al.
patent: 2002/0096631 (2002-07-01), Andrien et al.
patent: 09-292368 (1997-11-01), None
patent: 2002-063865 (2002-02-01), None
“A New Approach for the Study of Gas-Phase Ion—Ion Reactions Using Electrospray Ionization” Rachel R. Ogorzalek Loo, et al., 1992 American Society for Mass Spectrometry.
Stephenson, Jr., et al., “ Ion/Ion Proton Transfer Reactions for Protein Mixture Analysis”, Analytical Chemistry, vol. 68, No. 22, Nov. 15, 1996, pp. 4026-4032.
Stephenson, Jr., et al., “ Adaptation of the Paul Trap for Study of the Reaction of Multiply Charged Cations with Singly Charged Anions” International Journal of Mass Spectometry and Ion Processes vol. 162, pp. 89-106 (1997).

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