Mass spectrometer ion guide providing axial field, and method

Radiant energy – Ionic separation or analysis – Cyclically varying ion selecting field means

Reexamination Certificate

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C250S281000, C250S282000, C250S3960ML, C250S42300F, C250S424000

Reexamination Certificate

active

07868289

ABSTRACT:
An ion guide includes a plurality of rods, arranged about an axis that extends lengthwise from one end to the other of the guide. The rods guide ions in a guide region along and about the axis. A conductive casing surrounds the rods. The casing and the rods are geometrically arranged to produce an axial electric field along the axis. Specifically, the geometry is such that a first constant applied DC voltage (UDC), applied to the rods, and a second constant applied DC voltage (UCASE) applied to the casing, produce a voltage gradient between said casing and said axis that has a different magnitude at different positions along said axis.

REFERENCES:
patent: 4023398 (1977-05-01), French et al.
patent: 4234791 (1980-11-01), Enke et al.
patent: 4531056 (1985-07-01), Labowsky et al.
patent: 4842701 (1989-06-01), Smith et al.
patent: 4861988 (1989-08-01), Henion et al.
patent: 4885076 (1989-12-01), Smith et al.
patent: 4963736 (1990-10-01), Douglas et al.
patent: 4977320 (1990-12-01), Chowdhury et al.
patent: 5015845 (1991-05-01), Allen et al.
patent: 5103093 (1992-04-01), Sakairi et al.
patent: 5171990 (1992-12-01), Mylchreest et al.
patent: 5248875 (1993-09-01), Douglas et al.
patent: 5352892 (1994-10-01), Mordehai et al.
patent: 5412208 (1995-05-01), Covey et al.
patent: 5521382 (1996-05-01), Tanaka et al.
patent: 5756994 (1998-05-01), Bajic
patent: 5847386 (1998-12-01), Thomson et al.
patent: 6107628 (2000-08-01), Smith et al.
patent: 6111250 (2000-08-01), Thomson et al.
patent: 6124675 (2000-09-01), Bertrand et al.
patent: 6462336 (2002-10-01), Bajic
patent: 6462338 (2002-10-01), Inatsugu et al.
patent: 6674071 (2004-01-01), Franzen et al.
patent: 6700119 (2004-03-01), Giles
patent: 6707037 (2004-03-01), Whitehouse
patent: 6730904 (2004-05-01), Wells
patent: 6744043 (2004-06-01), Loboda
patent: 6753523 (2004-06-01), Whitehouse et al.
patent: 6872938 (2005-03-01), Makarov et al.
patent: 6914241 (2005-07-01), Giles et al.
patent: 7064322 (2006-06-01), Crawford et al.
patent: 7164125 (2007-01-01), Weiss et al.
patent: 7507955 (2009-03-01), Crawford et al.
patent: 7564025 (2009-07-01), Crawford
patent: 2003/0136905 (2003-07-01), Franzen et al.
patent: 2003/0222213 (2003-12-01), Taniguchi
patent: 2004/0011956 (2004-01-01), Londry et al.
patent: 2005/0274887 (2005-12-01), Weiss et al.
patent: 2007/0164213 (2007-07-01), Javahery et al.
patent: 2008/0203287 (2008-08-01), Crawford
patent: 2 324 906 (1998-04-01), None
Dawson, P.H., ed., “Quadrupole Mass Spectrometry and its Applications”, 1976, pp. 1-63, Elsevier Scientific Publishing, Amsterdam.
McFarland, M.A. et al., “Ion ‘Threshing’: Collisionally Activated Dissociation in an External Octopole Ion Trap by Oscillation of an Axial Electric Potential Gradient”, Analytical Chemistry, 2004, pp. 1545-1549, vol. 76.
Javahery, G. and B. Thomson, “A Segmented Radiofrequency-Only Quadrupole Collision Cell for Measurements of Ion Collision Cross Section on a Triple Quadrupole Mass Spectrometer”, J. Am. Soc. Mass. Spectrom., 1997, pp. 697-702, vol. 8.
March, Raymond E. and John F. Todd, eds., “Practical Aspects of Ion Trap Mass Spectrometry, vol. 1: Fundamentals of Ion Trap Mass Spectrometry”, 1995, pp. 10, 210-213, CRC Press, Inc.
March, Raymond E. and John F. Todd, eds., “Practical Aspects of Ion Trap Mass Spectrometry, vol. 2: Ion Trap Instrumentation”, 1995, pp. 90-95, CRC Press, Inc.
Ashcroft, Alison E., “Ionization Methods in Organic Mass Spectrometry”, The Royal Society of Chemistry Analytical Spectroscopy Monographs, 1997, pp. 20-26, 61-65, 74-83, 98-106, 122-127, 132-139, The Royal Society of Chemistry, Cambridge, UK.
Dehmelt, H.G., “Radiofrequency Spectroscopy of Stored Ions I: Storage”, Advances in Atomic Physics 3, 1967, pp. 53-72.
Zubarev, Roman A. et al., “Electron Capture Dissociation of Multiply Charged Protein Cations. A Nonergodic Process”, American Chemical Society, 1998, pp. 3265-3266, vol. 120.
Gerlich, Dieter, “Inhomogeneous RF Fields: A Versatile Tool for the Study of Processes with Slow Ions”, Advances in Chemical Physics, 1992, pp. 1-176, vol. 82, Johny Wiley & Sons, Ltd.
Mason, Edward A. and Earl W. McDaniel, “Transport Properties of Ions in Gases”, 1988, pp. 11-27, 468-479, John Wiley & Sons, Inc., New York.
Herron, William J. et al., “Reactions of Polyatomic Dianions with Cations in the Paul Trap”, Rapid Commun. Mass Spectrometry, 1996, pp. 277-281, vol. 10, John Wiley & Sons, Ltd.
Cole, Richard B. ed., “Electrospray Ionization Mass Spectrometry: Fundamentals, Instrumentation and Applications”, May 1997, pp. 179-196, 204-230, 244-250, John Wiley & Sons, Ltd.
International Search Report for International Patent Application No. PCT/CA2007/000049, filed Jan. 11, 2007.
Lee, E.D. and J.D. Henion, “Thermally Assisted Electrospray Interface for Liquid Chromatography/Mass Spectrometry”, Rapid Communication in Mass Spectrometry, 1992, pp. 727-733, vol. 6.
International Search Report for International Patent Application No. PCT/CA2008/000776, filed Apr. 24, 2008.

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