Mass spectrometer interface

Radiant energy – Ionic separation or analysis – With sample supply means

Reexamination Certificate

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Details

C250S284000, C250S286000, C250S287000, C250S281000

Reexamination Certificate

active

07405398

ABSTRACT:
A mass spectrometer interface, having improved sensitivity and reduced chemical background, is disclosed. The mass spectrometer interface provides improved desolvation, chemical selectivity and ion transport. A flow of partially solvated ions is transported along a tortuous path into a region of disturbance of flow, where ions and neutral molecules collide and mix. Thermal energy is applied to the region of disturbance to promote liberation of at least some of the ionized particles from any attached impurities, thereby increasing the concentration of the ionized particles having the characteristic m/z ratios in the flow. Molecular reactions and low pressure ionization methods can also be performed for selective removal or enhancement of particular ions.

REFERENCES:
patent: 4023398 (1977-05-01), French et al.
patent: 4531056 (1985-07-01), Labowsky et al.
patent: 4842701 (1989-06-01), Smith et al.
patent: 4861988 (1989-08-01), Henion et al.
patent: 4885076 (1989-12-01), Smith et al.
patent: 4948962 (1990-08-01), Mitsui et al.
patent: 4977320 (1990-12-01), Chowdhury et al.
patent: 4990740 (1991-02-01), Meyer
patent: 5015845 (1991-05-01), Allen et al.
patent: 5070240 (1991-12-01), Lee et al.
patent: 5103093 (1992-04-01), Sakairi et al.
patent: 5171990 (1992-12-01), Mylchreest et al.
patent: 5229605 (1993-07-01), Bridenne et al.
patent: 5313061 (1994-05-01), Drew et al.
patent: 5352892 (1994-10-01), Mordehai et al.
patent: 5412208 (1995-05-01), Covey et al.
patent: 5454274 (1995-10-01), Zhu
patent: 5756994 (1998-05-01), Bajic
patent: 6124675 (2000-09-01), Bertrand et al.
patent: 6252225 (2001-06-01), Takada et al.
patent: 6265717 (2001-07-01), Sakata et al.
patent: 6462336 (2002-10-01), Bajic
patent: 6700119 (2004-03-01), Giles
patent: 6781117 (2004-08-01), Willoughby et al.
patent: 7098452 (2006-08-01), Schneider et al.
patent: 2002/0003210 (2002-01-01), Marcus
patent: 2003/0062474 (2003-04-01), Baranov et al.
patent: 2004/0262512 (2004-12-01), Tobita et al.
patent: 2006/0118715 (2006-06-01), Schneider et al.
patent: 2 324 906 (1998-04-01), None
patent: 2324906 (1998-11-01), None
R.A. Zubarev, et al., “Electron Capture Disassociation of Multiply Charged Protein Cations. A Nonergodic Process”,J. Am. Chem. Soc., 120, 3265-3266 (1998).
Edgar D. Lee, et al., “Thermally Assisted Electrospray Interface for Liquid Chromatograph/ Mass Spectrometry”,Rapid Communication in Mass Spectrometry, vol. 6, 727-733 (1992).
William J. Herron et al., “Reactions of Polyatomic Dianions with Cations in the Paul Trap”, Chemical and Analysis Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, 5 pgs. (1995).

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