Mass spectrometer and mass spectrometric analysis method

Radiant energy – Ionic separation or analysis – Methods

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C250S281000, C250S283000, C250S287000, C250S288000, C250S290000, C250S291000, C250S292000, C250S299000

Reexamination Certificate

active

07956322

ABSTRACT:
An MS/MS spectrometric analysis method obtains throughput and mass resolving power of precursor ions. In a mass spectrometer, ions, which are introduced and accumulated in an ion trap unit, are resonance-extracted mass-selectively. A profile of precursor ions at the m/z axis of the ion trap and a profile at the mass analyzer portion, which performs mass analysis of the ions extracted from a collision induced dissociation portion, is obtained by performing a measurement when the injection energy to the collision induced dissociation portion is low, and when the injection energy to the collision induced dissociation portion is high. The profile at the m/z axis of the ion trap of the obtained two-dimensional spectrum is substituted with the profile at the m/z axis of the mass analyzer portion. In this way, the m/z of both the precursor ions and the fragment ions can be determined with high mass resolving power.

REFERENCES:
patent: 5464985 (1995-11-01), Cornish et al.
patent: 6504148 (2003-01-01), Hager
patent: 6507019 (2003-01-01), Chernushevich et al.
patent: 7078685 (2006-07-01), Takada et al.
patent: 7348554 (2008-03-01), Hashimoto et al.
patent: 7569814 (2009-08-01), Hashimoto et al.
Donald F. Hunt, et al. “Sequence Analysis of Polypeptides by Collision Activated Dissocation on a Triple Quadrupole Mass Spectrometer”, Biomedical Mass Spectrometry Magazine, vol. 8, No. 9, pp. 397, 1981.
Howard R. Morris, et al, “High Sensitivity Collisionally-activated Decomposition Tandem Mass Spectrometry on a Novel Quadrupole/Orthogonal-acceleration Time-of-flight Mass Spectrometer”, Rapid Communications in Mass Spectometry Magazine, vol. 10, pp. 889-866, 1996.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Mass spectrometer and mass spectrometric analysis method does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Mass spectrometer and mass spectrometric analysis method, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mass spectrometer and mass spectrometric analysis method will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2742244

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.