Mass spectrometer

Radiant energy – Ionic separation or analysis

Reexamination Certificate

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Details

C250S282000

Reexamination Certificate

active

06992281

ABSTRACT:
An Inductively Coupled Plasma (“ICP”) mass spectrometer is disclosed comprising a mass filter and a reaction/collision cell. Analyte ions and background ions having the same nominal mass to charge ratio are transmitted by the mass filter. The analyte ions selectively react with gas in the reaction/collision cell to form product ions having different mass to charge ratios. By measuring the intensity of the product ions the intensity of the analyte ions can be determined. According to less preferred embodiments background ions may be neutralised or reacted in the reaction/collision cell.

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Bateman et al., “A Novel Precursor Ion Discovery Method on a Hybrid Quadrupole Orthogonal Acceleration Time-of-Flight (Q-TOF) Mass Spectrometer for Studying Protein Phosphorylation”, Journal of American Society Mass Spectrometry, vol. 13, pp. 792-803, 2002.

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