Radiant energy – Ionic separation or analysis – With sample supply means
Reexamination Certificate
2006-12-05
2011-11-15
Vanore, David A (Department: 2881)
Radiant energy
Ionic separation or analysis
With sample supply means
C250S281000, C250S282000, C250S287000
Reexamination Certificate
active
08058610
ABSTRACT:
A sample plate3with a sample4placed thereon is initially set on a stage2, and a visual image of the sample is taken with a CCD camera14. This image is stored in an image data memory23. Then, an operator removes the sample plate3, sprays a matrix for a MALDI process onto the sample4and replaces the plate onto the stage2. After that, when a predetermined operation is made, a clear image of the sample taken before the application of the matrix is shown on a display unit24. On this image, the operator specifies a point or area for the analysis. The sample4may have been displaced due to the removal and replacement of the plate3. Accordingly, an image analyzer44calculates the direction and magnitude of the displacement, for example, by recognizing the position of the markings provided on the sample plate3. A displacement corrector42computes coordinate values in which the displacement is corrected. Thus, even if a displacement occurs, the mass analysis can be accurately performed on the point or area of the actual sample as specified on the clear visual image taken before the application of the matrix.
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Written Opinion of the International Searching Authority dated Mar. 13, 2007, issued in corresponding International application No. PCT/JP2006/324259.
Harada Takahiro
Ogawa Kiyoshi
Setou Mitsutoshi
Takeuchi Sadao
Shimadzu Corporation
Sughrue & Mion, PLLC
Vanore David A
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