Mass spectrometer

Details Mass spectrometer Mass spectrometer

2005-09-16

2010-10-12

Berman, Jack I (Department: 2881)

Radiant energy

Ionic separation or analysis

With sample supply means

C250S281000, C250S282000, C250S285000, C250S43200R, C250S292000

Reexamination Certificate

active

07812308

ABSTRACT:
In a liquid chromatograph mass spectrometer having an ionization interface capable of simultaneously performing ionization operations by ESI and APCI, a spray nozzle22for spraying a liquid sample given form a liquid chromatograph section as charged droplets, and a corona discharger25for ionizing mobile phase solvent molecules are placed in the same ionization chamber21. The same voltages are applied to both the spray nozzle and the corona discharger from a single high-voltage power supply41. The electrical power's value of the heater27of the heated dry gas supplier for drying the charged droplets generated in the spray nozzle22are set to be suitable for the ionization according to APCI. Consequently, the labor for the circuit design and the number of the parts are reduced. At the same time, the parameter setting items for the user are decreased, which leads to enhanced operability.

REFERENCES:
patent: 5668370 (1997-09-01), Yano et al.
patent: 6646257 (2003-11-01), Fischer et al.
patent: 2000-088808 (2000-03-01), None
patent: 2002-157971 (2002-05-01), None
patent: 2004-185886 (2004-07-01), None
patent: 2004-294453 (2004-10-01), None
patent: 2005-528746 (2005-09-01), None
patent: 03/102537 (2003-12-01), None
M. M. Siegel et al.: “Evaluation of a Dual Electrospray Ionization/Atmospheric Pressure Chemical Ionization Source at Low Fow Rates (˜ 50 muL/min) for the Analysis of Both Highly and Weakly Polar Compounds” Journal of the American Society for Mass Spectrometry, Elsevier Science Inc, US, vol. 9, No. 11, Nov. 1, 2008, pp. 1196-1203, XP004142529, ISSN: 1044-0305.
R. King et al.: “Mechanistic investigation of ionization suppression in electrospray ionization” Journal of the American Society for Mass Spectrometry, Elsevier Science Inc, US, vol. 11, No. 11, Nov. 1, 2000, pp. 942-950, XP004224829, ISSN: 1044-0305.
Daniel D. Ebeling, et al., “Corona Discharge in Charge Reduction Electrospray Mass Spectrometry”, Anal. Chem., 2000.11.1, vol. 72, No. 21, p. 5158-5161.

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