Mass analysis with alternating bypass of a fragmentation device

Radiant energy – Ionic separation or analysis – With sample supply means

Reexamination Certificate

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Details

C250S281000, C250S282000, C250S284000, C250S286000, C250S290000

Reexamination Certificate

active

07851751

ABSTRACT:
A method for analyzing a mixture of components includes forming precursor ions from the components, alternately causing the precursor ions to pass to and to by-pass a fragmentation device, to form product ions from the precursor ions that pass to the device and to form substantially fewer product ions from precursor ions that by-pass the device, and obtaining mass spectra from product ions received from the device and from precursor ions that by-passed the device. An apparatus for analyzing a sample includes an ion source for forming precursor ions from the components of the sample, a fragmentation device for forming product ions from the precursor ions, a by-pass device disposed upstream of the fragmentation device for switchable by-pass of the fragmentation device, and a mass analyzer.

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patent: 7417226 (2008-08-01), Bajic et al.
patent: 7759638 (2010-07-01), Makarov
patent: 2007/0114439 (2007-05-01), Bajic et al.
patent: 2008/0224033 (2008-09-01), Makarov
patent: 2009/0065690 (2009-03-01), Bateman
patent: 2009/0206248 (2009-08-01), Makarov et al.
patent: 2009/0272895 (2009-11-01), Makarov

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