Markers for detection of chromosome 16 rearrangements

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 912, 436 63, 436 64, 536 235, 536 2431, 536 2433, 935 6, 935 8, 935 9, 935 78, H04N 132

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058374574

ABSTRACT:
The breakpoints of the pericentric inversion of chromosome 16 have been cloned. Two genes, one at each breakpoint, have also been identified, as well as several forms of the inversion 16 fusion gene. Diagnostic applications for chromosome 16 abnormalities and, particularly acute myeloid leukemia are also within the scope of the present invention.

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