Marker peptide for alzheimer's disease

Details Marker peptide for alzheimer's disease Marker peptide for alzheimer's disease

2004-11-01

2010-10-05

Chernyshev, Olga N (Department: 1649)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

C530S324000, C530S326000, C435S007100, C435S007900, C435S007920

Reexamination Certificate

active

07807777

ABSTRACT:
To provide a peptide obtainable by cleaving an N-terminal region and a C-terminal region of Alcadein α, Alcadein β, or Alcadein γ; and capable of being a diagnostic marker for Alzheimer's disease. It is possible to detect Alzheimer's disease at an early stage without burdening subjects to be tested by using the peptide as a diagnostic marker.

REFERENCES:
patent: 2003-164298 (2003-06-01), None
patent: WO-02/22819 (2002-03-01), None
patent: WO-02/22819 (2002-03-01), None
Yoichi Araki et al.; The Journal of Biological Chemistry, vol. 278, No. 49, pp. 49448-49458, Dec. 5, 2003.
Yoichi Araki et al.; The Journal of Biological Chemistry, vol. 279, No. 23, pp. 24343-24354, Jun. 4, 2004.
Vogt, Lorenz et al.; Molecular and Cellular Neurosciences, vol. 17, pp. 151-166 (2001).

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