Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2011-01-04
2011-01-04
Cheu, Jacob (Department: 1641)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C436S518000
Reexamination Certificate
active
07863007
ABSTRACT:
The present invention relates to amniotic fluid specific polypeptide and a method for detecting rupture of the amniotic membranes. In particular the invention provides a marker for prolonged rupture of the membranes (PROM), which marker consists essentially of polypeptides of approximately 75 kDa, 20 kDa and 50 kDa as determined by 4-15% gradient SDS-PAGE under reducing conditions.
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patent: WO92/10585 (1992-06-01), None
patent: WO 94/21687 (1994-09-01), None
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Thadikkaran et al., “The role of proteomics in the assessment of premature rupture of fetal membranes,”Clinica Chimica Acta, Oct. 2005, pp. 27-36, vol. 360.
Guibourdenche, et al., “Rapid detection of insulin-like growth factor-binding protein-1 and foetal fibronectin in cervivo-vaginal secretions to diagnose premature membrane rupture,”Annals of Clinical Biochemistry, 1999, pp. 388-390, vol. 37, No. 3.
Gaucherand, et al., “Comparative study of three amniotic fluid markers in premature rupture of membranes: fetal fibronectic, alpha-fetoprotein, diamino-oxydase.”Acta Obstetricia et Gynecologica Scandinavica, Feb. 1995, pp. 118-121, vol. 74, No. 2.
Vuadens, et al., “Identification of biologic markers of the premature rupture of fetal membranes: Proteomic approach,” Proteomics, 2003, pp. 1521-1525, vol. 3.
Alston & Bird LLP
Cheu Jacob
Swiss Asian Property Limited
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