Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1988-04-20
1990-05-01
Warden, Robert J.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
4351722, 43524026, 43524027, 435810, 436501, 436512, 436548, 436808, 436813, 436815, 530395, 530828, 530843, G01N 3353, G01N 33566, G01N 33563, C12M 1500
Patent
active
049217895
ABSTRACT:
A new marker for colorectal carcinoma has been discovered which is a glycoprotein having a molecular weight of approximately 160,000 daltons. Assay methods which can identify this marker are useful indetecting, diagnosing, and monitoring colorectal carcinoma, and in particular, carcinoma of the undifferentiated variety which heretofor were not readily detectible. For example, an assay which utilizes an antibody reacting to this glycoprotein marker is useful in a screening method for the detection and monitoring of colorectal carcinoma cells. Such an antibody can be included as part of a kit for screening a patient for colorectal carcinoma.
REFERENCES:
patent: 4363799 (1982-12-01), Kung et al.
patent: 4489167 (1984-12-01), Ochi et al.
patent: 4579827 (1986-04-01), Sakamoto et al.
patent: 4818682 (1989-04-01), Linnane
Blaszczyk, M. et al., Cancer Research 44: 245-253 (1984).
DeLellis et al., (1987), Seminars in Oncology 14: 173-192.
Niles et al., (1987), Cancer Investigation 5: 545-552.
Schoentag et al., (1987), Cancer Research 47: 1695-1700.
Vecchi et al., (1987), Proc. Natl. Acad. Sci., U.S.A., 84: 3425-3429.
Abe et al., (1986), Cancer Research 46: 2639-2644.
Bleday et al., (1986), Cancer 57: 433-440.
Itzkowitz et al., (1986), Cancer Reserach 46: 2627-2632.
Rogers et al., (1986), Cancer Immunol. Immunother, 23: 107-112.
Sakamoto et al., (1986), Cancer Reserach 46: 1553-1561.
Yuan et al., (1985), Cancer Reserach 45: 4499-4511.
Nadakavukaren et al., (1984), Differentiation 27: 209-220.
Fredman et al., (1983), The Journal of Biological Chemistry 258: 11206-11210.
Wagener et al., (1983), The Journal of Immunology 130: 2308-2315.
Herlyn et al., (1982), Proc. Natl. Acad, Sci., U.S.A., 79: 4761-4765.
Kurzinger et al., (1982), The Journal of Biological Chemistry 257: 12412-12418.
Goslin et al., (1981), The American Journal of Medicine 71: 246-253.
Hsu et al., (1981), The Journal of Histochemistry and Cytochemistry 29: 1349-1353.
Kupchik et al., (1981), Cancer Research 41: 3306-3310.
Morrison, (1980), Methods in Enzymology 70: 214-220.
Herlyn et al., (1979), Eur. J. Immunol. 9: 657-659.
Springer et al., (1979), Journal of Surgical Oncology 11: 95-106.
Ey et al., (1978), Biochemistry 15: 429-436.
Springer et al., (1977), Clinical Immunology and Immunopathology 7: 426-441.
Search Report (Paper Chase) Relating Generally to the Field of Tumor-Specific Antigens.
Salem et al., (1987), Surgical Forum (Oct.) pp. 408-410.
Salem et al., (1987), Proceedings of AACR, vol. 28--Immunology, Abstract No. 1571.
Salem Ronald R.
Steele Glenn
Thomas Peter
New England Deaconess Hospital Corporation
Spiegel Jack
Warden Robert J.
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