Marek's disease herpesvirus DNA segments encoding glycoproteins,

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 241, C07H 2104

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active

058666974

ABSTRACT:
DNA encoding glycoproteins gD, gI and part of gE from Marek's disease herpesvirus is described. The DNA is useful for probes to detect the DNA in the herpesvirus, for expression to produce the glycoproteins can be used for producing the antibodies which specifically recognize the three glycoprotein antigens, and in the case of the latter two genes, for potential insertion sites for foreign genes. Novel glycoproteins and regulatory sequences are also disclosed.

REFERENCES:
Fukuchi et al. Journal of Virology, Jul. 1984, vol. 51 No. 1, pp. 102-109.
Cebrian et al. Proc. Natl. Acad. Sci USA, Jan. 1982 vol. 79 pp. 555-558.
McGeach et al. J. Mol. Biol., 1985, vol. 181 pp. 1-13.

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