Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...
Reexamination Certificate
2005-05-10
2005-05-10
Page, Thurman K. (Department: 1615)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Web, sheet or filament bases; compositions of bandages; or...
C424S449000, C424S402000, C424S489000, C424S484000, C424S464000
Reexamination Certificate
active
06890552
ABSTRACT:
Devices and methods for enhancing the healing of wounds, especially chronic wounds (e.g., diabetic wounds), involving the use of keratinocytes are described. Keratinocytes are grown on a transplantable solid support (e.g., collagen-coated beads), and the keratinocyte-coated solid support is placed in an enclosure. The enclosure, in turn, is placed in the wound for use as an interactive wound healing promoter.
REFERENCES:
patent: 4576715 (1986-03-01), Michaels et al.
patent: 4997443 (1991-03-01), Walthall et al.
patent: 5269917 (1993-12-01), Stankowski
patent: 5294446 (1994-03-01), Schlameus et al.
patent: 5334527 (1994-08-01), Brysk
patent: 5459069 (1995-10-01), Palsson
patent: 5487889 (1996-01-01), Eckert et al.
patent: 5512474 (1996-04-01), Clapper et al.
patent: 5529914 (1996-06-01), Hubbell et al.
patent: 5545423 (1996-08-01), Soon-Shiong et al.
patent: 5554423 (1996-09-01), Abate
patent: 5563068 (1996-10-01), Zhang et al.
patent: 5643773 (1997-07-01), Aebischer et al.
patent: 5693332 (1997-12-01), Hansbrough
patent: 5712163 (1998-01-01), Parenteau et al.
patent: 5741685 (1998-04-01), Vacanti
patent: 5830507 (1998-11-01), Armstrong
patent: 5972332 (1999-10-01), Rees et al.
patent: 2010028 (1994-03-01), None
patent: WO 8803785 (1988-02-01), None
patent: WO 9612510 (1996-05-01), None
T.K. Hunt and W.H. Goodson III, “Wound Healing,”Current Surgical Diagnosis&Treatment(Way; Appleton & Lange), pp. 86-98 (1988).
Richey et al., “Topical Growth Factors and Wound Contraction in the Rat: Part 1. Literature Review and Definition of the Rat Model,” Ann. of Plastic Surgery 23(2):159-165 (1989).
G.D. Winter, “Formation of the Scab and the Rate of Epithelization of Superficial Wounds in the Skin of the Young Domestic Pig,”Nature, 193:293-94 (1962).
G.A. Kannon and A.B. Garett, “Moist Wound Healing wth Occlusive Dressings: A Clinical Review,”Dermatol. Surg., 21:583-590 (1995).
J.W.L. Davies, “Synthetic materials for covering burn wounds: Progress towards perfection. Part II. Longer term substitutes for skin,”Burns, 10:94-103 (1983).
Riley, “Wound Healing,”Am. Fam. Physician, 24:107-113 (1981).
S.T. Boyce et al., “Skin wound closure in athymic mice with cultured human cells, biopolymers, and growth factors,”Surgery, 110:866-76 (1991).
A. Barbul et al., “Wound healing in nude mice: A study on the regulatory role of lymphocytes in fibroplasia,”Surgery, 105:764-69 (1989).
J.F. Hansbrough et al., “Composite Grafts of Human Keratinocytes Grown on a Polyglactin Mesh-Cultured Fibroblast Dermal Substitute Function as a Bilayer Skin Replacement in Full-Thickness Wounds on Athymic Mice,”J. Burn Care Rehabil., 14:485-94 (1993).
B.A. Gilchrest et al., “Growth of Human Keratinocytes on Fibronectin-Coated Plates,”Cell Bio. Int. Rep.4(11):1009-1016 (1980).
I.A. Schafer et al.,“The Interaction of Human Papillary and Reticular Fibroblasts and Human Keratinocytes in the Contraction of Three-Dimensional Floating Collagen Lattices,”Exp. Cell. Res., 183:112-125 (1989).
J.R. Cook and R.G. van Buskirk, “The Matrix of Collagen and Basal Microporosirty Influence Basal Lamina Deposition and Laminin Synthesis/Secretion by Stratified Human Keratinocytes In Vitro,” In VitroCell Dev. Biol., 31:132-139 (1995).
J.F. Hansbrough et al.,“Burn Wound Closure with Autologous Keratinocytes and Fibroblasts Attached to a Collagen-Glycosaminoglycan Substrate,”J. Am. Med. Assoc., 262:2125-2130 (1989).
M.L. Cooper et al., “In Vitro Effects of Matrix Peptides on a Cultured Dermal-Epidermal Skin Substitute,”J. Surg. Res., 48:528-533 (1990).
V. Ronfard et al., “Use of human keratinocytes cultured on fibrin glue in the treatment of burn wounds,”Burns, 17:181-184 (1991).
E. Tinois et al., “In Vitro and Post-transplantation Differentiation of Human Keratinocytes Growth on the Human Type IV Collagen Film of a Bilayered Dermal Substitute,”Exp. Cell Res., 193:310-319 (1991).
J. Nanchahal and C.M. Ward, “New grafts for old? A review of alternative to autologous skin,”Brit. J. Plas. Surg., 45:354-363 (1992).
Van der Merve et al., “Allografted keratinocytes used to accelerate the treatment of burn wounds are replaced by recipient cells,”Burns, 16:193-197 (1990).
Boyce and Ham, “Normal human epidermal keratinocytes,” In VitroModels for Cancer Research(Weber and Sekely, eds.) CRC Press, Boca Raton, FL, pp. 245-274 (1985).
Pharmacia Catalog, pp. 26-27.
ICN Catalog ,ICN Biomedical Research Products, pp. 130-131.
Sigma Catalog, pp. 144-145.
N. Carver et al., “The effect of backing materials on keratinocyte autograft take,” Brit. J. of Plastic Surgery, 46:228-234 (1993).
J.F. Woessner, Jr., “Matrix metalloproteinases and their inhibitors in connective tissue remodeling,”FASEBJ., 5:2145-2154 (1991).
Green et al., “Growth of Cultured human epidermal cells into mulitple epithelia suitable for grafting,”Proc. Nat. Acad. Sci.76: 5665-5668 (1979).
Leigh et al., “Treatment of chronic venous ulcers with sheets of cultured allogenic keratinocyted,”Brit. J. Derm117:591-597 (1987).
Takashima et al., “Activation of Rabbit Keratinocyte Fibronectin Receptor Function In Vivo During Wound Healing,”J. Invest. Derm.86:585-590 (1986).
Brown et al., “Enhancement of Epidermal Regeneration by Biosynthetic Epidermal Growth Factor,”J. Exp. Med.163:1319-1324 (1986).
Stompro, “Attachment of Growth Factors to Implantable Collagen,”Current Surgery47:35-37 (1990).
Jones et al.,“Current Research Review: Effect of Topical Recombinant TGF-β on Healing of Partial Thickness Injuries,”J. Surg. Res.51:344-352 (1991).
Schultz et al., “EGF and TGF-α in Wound Healing and Repair,”J. Cell. Biochem.45:346-352 (1991).
Myers et al., “Transplantation of Keratinocytes in the Treatment of Wounds,”Am. J. Surg.170:75-83 (1995).
Ejim et al., “Production of artificial-orientated mats and strands from plasma fibronectin: a morphological study,”Biomaterials14(10):743-748 (1993).
Schwarz et al., Wound Repiar and Regneration 3:204-212 (1995). At the present time we are unable to obtain a copy of this reference. If the Examiner needs this reference please contact our offices and we will obtain a copy.
He and McCulley, “Growth human corneal epithelium on collagen sheild and subsequent transfer to denuded cornea in vitro,”Curr. Eye Res.10(9):851-863 (1991).
Serdev, Fresh Keratinocytes Adhered On Collagen Micro-Carriers For Definitive Closure Of Atonic Chronic Wounds, International Journal Of Aesthetic Cosmetic Beauty Surgery, 2:7 (2002).
Adamson Belinda
Garner Warren
Gilmont Robert
Lindblad William J.
Marcelo Cynthia
Ghali Isis
Medlen & Carroll LLP
Page Thurman K.
Regents of the University of Michigan
Wayne State University
LandOfFree
Manufacturing therapeutic enclosures does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Manufacturing therapeutic enclosures, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Manufacturing therapeutic enclosures will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3426713