Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1996-06-26
1998-04-28
Tsang, Cecilia J.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
530412, 530416, 530380, 530395, 424 85, 514 8, 514724, A61K 3800, C07K 500, C07K 700, C07K 1600
Patent
active
057445869
ABSTRACT:
Method for obtaining highly purified transferrin from a partially purified plasma fraction containing transferrin in which the starting fraction is concentrated. Its ionic strength is reduced and then transferrin is adsorbed onto a chromatographic column. Following elution, the transferrin can be further processed through to packaging in final containers. The final purified transferrin product is sterile, at least 95% pure and is substantially free of enveloped and non-enveloped viruses.
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patent: 5041537 (1991-08-01), Bethke et al.
Harris, et al., Protein Purification Methods A Practical Approach, pp. 5-9, 126-148, 1989.
Soliman, et al., A Medium Scale Method for the Purification of Human Serum Transferrin and IgG Globulin by Chromatographic Technique, U.A.R. J. Chem., vol. 14, No. 2, pp. 177-183, 1971.
Bhattacharya Prabir
Latham Shawn D.
Ohmizu Akimasa
Rolf John M.
Alpha Therapeutic Corporation
Harle Jennifer
Tsang Cecilia J.
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