Manufacturing method of microcapsule using phospholipid

Details Manufacturing method of microcapsule using phospholipid Manufacturing method of microcapsule using phospholipid

1995-11-20

1998-06-30

Mullis, Jeffrey C.

Plastic and nonmetallic article shaping or treating: processes

Encapsulating normally liquid material

Liquid encapsulation utilizing an emulsion or dispersion to...

4272133, B01J 1300, B01J 1304

Patent

active

057729298

ABSTRACT:
The invention relates to a method of manufacturing microcapsules (fat emulsion or liposome) of high stability and smaller mean particle size with a smaller energy and in a shorter treating time. Prior to dispersing a phospholipid treating liquid in a high speed rotary dispersing machine, a treating tank of the high speed rotary dispersing machine is filled up with only the treating liquid. Dispersion of the treating liquid is conducted by rotating at high speed while the treating tank is pressurized to reduce cavitation generation. For precision dispersion of this treating liquid, it is transferred into a precision dispersion apparatus, such as high pressure homogenizer, without contacting with a gas phase. The method reduces the mean particle size of the microcapsules to increase their stability for a long time period.

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