Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-12-26
2006-12-26
McKane, Joseph K. (Department: 1626)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
active
07153984
ABSTRACT:
A process for the manufacture of (all-rac)-α-tocopherol by the acid-catalyzed reaction of trimethylhydroquinone with isophytol or phytol is characterized by carrying out the reaction in the presence of methane trisulphonate as the catalyst in an organic solvent. The product of the process is the most active and industrially most important member of the vitamin E group.
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Ishihara, K. et al., “Practical Synthesis of (±)-α-Tocopherol. Trifluoromethanesulfonimide as an Extremely Active Bronsted Acid Catalyst for the Condensation of Trimethylhydroquinone with Isophytol,”Synlett, vol. 11, pp. 1045-1046 (1996).
Sartori, P. and Jüschke, R., “Verbessertes Verfahren zur Darstellung des tri-Kalium-methantrisulfonat-Monohydrates,”J. Prakt. Chem., vol. 336, pp. 373-374 (1994).
Jüschke, R. and Sartori, P., “Untersuchungen zur Säurestärke von Alkanpolysulfonsäuren,”Z. Naturforsch, vol. 51b, pp. 1691-1700 (1996).
Hall, J.R. et al., “Crystal Structure, and the Infrared and Raman Spectra, of Tripotassium Methanetrisulphonate Hydrate, K3[CH(SO3)3]•H2O,”J.C.S. Dalton, pp. 149-155 (1980).
Bonrath Werner
Haas Alois
Hoppmann Simone
Netscher Thomas
Pauling Horst
Barker Michael P.
Bryan Cave LLP
DSM IP Assets B.V.
McKane Joseph K.
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