Manufacture of test strips

Details Manufacture of test strips Manufacture of test strips

1997-09-23

2000-10-10

Chin, Christopher L.

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

422 56, 422 57, 422 58, 435 4, 4352871, 4352872, 4352877, 4352879, 435805, 435810, 435970, 436169, 436514, 436530, 436810, G01N 33543

Patent

active

061301000

ABSTRACT:
A process of manufacturing test strips of the type comprising a length of porous carrier material capable of acting as a liquid flow path for a sample liquid and having at least zone downstream from a first end of the strip which zone contains an immobilized specific binding agent to act as a capture means during an assay to reveal the presence of an analyte in applied sample liquid, and in which process the specific binding agent is deposited onto a sheet of the porous carrier material which is then blocked and subdivided into a plurality of individual identical test strips, wherein blocking of the porous carrier material is achieved by applying a solution of blocking agent to the sheet upstream from the zone in an amount sufficient to ensure that the solution permeates downstream to beyond the zone. Preferably there is a plurality of zones of immobilized agent arranged in series on the strip, and wherein blocking is achieved by applying a solution of blocking agent to the sheet upstream from the first of the plurality of zones in an amount sufficient to ensure that the solution permeats downstream to beyond the last of the plurality of zones.

REFERENCES:
patent: 4235601 (1980-11-01), Deutsch et al.
patent: 5602040 (1997-02-01), May et al.

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