Manufacture of tartrate disuccinate/tartrate monosuccinate with

Details Manufacture of tartrate disuccinate/tartrate monosuccinate with Manufacture of tartrate disuccinate/tartrate monosuccinate with

1990-06-26

1991-05-14

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Dentifrices

Hydroxy carboxylic acid or derivative thereof

A61K 724

Patent

active

050154680

ABSTRACT:
Mixtures of tartrate disuccinate and tartrate monosuccinate enriched in the disuccinate species are prepared by reacting isomerically pure D- or L-tartaric acid with maleic anhydride in the presence of sodium hydroxide and calcium hydroxide.

REFERENCES:
patent: 4452820 (1984-06-01), D'Amelia et al.
patent: 4582709 (1986-04-01), Peters et al.
patent: 4663071 (1987-05-01), Bush et al.
patent: 4689167 (1987-08-01), Collins et al.
patent: 4721580 (1988-01-01), Gosselink
patent: 4877896 (1989-10-01), Maldonado et al.
patent: 4904824 (1990-02-01), Horng et al.
patent: 4925586 (1990-05-01), Baker et al.
patent: 4959409 (1990-09-01), Heinzman et al.
patent: 4968451 (1990-11-01), Scheibel et al.

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