Manufacture of pharmaceutical dosage forms

Adhesive bonding and miscellaneous chemical manufacture – Methods – Surface bonding and/or assembly therefor

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424 21, 424 27, A61K 970

Patent

active

041659988

ABSTRACT:
Pharmaceutical dosage forms comprising an edible web having deposited thereon or at least partially thereon a particulate medicament, the webs being thereafter fabricated and finished to pharmaceutically elegant solid dosage forms having no medicament exposed on an exterior surface. The dosage forms have a consistency of release of medicament which can be controlled to exacting specifications. The disclosed solid dosage forms are prepared by high speed automated equipment and the process by which they are made is characterized by non-destructive quality control analysis and performance evaluation both conducted on-line and integrated into the manufacturing operation. Included in the scope of the disclosed invention are certain apparatus and methods of manufacture.

REFERENCES:
patent: 2836291 (1958-05-01), Stroop
patent: 3007848 (1961-11-01), Stroop
patent: 3292208 (1966-12-01), Wood
patent: 3531827 (1970-10-01), Dragonette
patent: 3917414 (1975-11-01), Geis et al.
Raymond et al.: Second International Conference on Instrumentation and Automation in the Paper, Rubber and Plastics Industries, Brussels, May 24-28, 1971, paper 11.2.

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