Manufacture of macrocyclic polyethers

Details Manufacture of macrocyclic polyethers Manufacture of macrocyclic polyethers

1981-04-09

1984-03-06

Fan, Jane T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549347, 549353, 549377, C07D32300, C07D31912

Patent

active

044355823

ABSTRACT:
This invention deals with a process for the preparation of macrocyclic polyethers of the general formula: ##STR1## wherein x is 1-9; k is 0 or 1 and each R, which may be the same or different, represents a hydrogen atom or a lower alkyl or aryl group, or two R bonded to two adjacent carbon atoms form together with these carbon atoms a cyclic hydrocarbyl configuration, by reacting a compound of the general formula: ##STR2## with a sulphonyl halide in the presence of a base and a halogen-containing solvent, preferably chlorobenzene. The process is of special interest for the manufacture of 18-crown-6.

REFERENCES:
patent: 4172083 (1979-10-01), Cincotta et al.
Johns et al., Synthesis, 1976, pp. 515-516.
Lin et al., J. Chem. Soc. Chem. Comm., 1978, pp. 504-505.
Derwent Abstracts, 78278B/43, equivalent to Japanese Patent 54-119483.

Affiliated with

Also associated with

Rating

Manufacture of macrocyclic polyethers does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Manufacture of macrocyclic polyethers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Manufacture of macrocyclic polyethers will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-742763