Manufacture of hollow fine tubular drug delivery systems

Details Manufacture of hollow fine tubular drug delivery systems Manufacture of hollow fine tubular drug delivery systems

1986-08-21

1988-01-19

Thurlow, Jeffery

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

264 41, 264150, 264171, 26417714, 264204, 2642091, 26421114, 264344, 264561, 264562, 424468, 424486, 424501, 6048921, A61K 3174, B29C 4704, B29C 6318

Patent

active

047203846

ABSTRACT:
Pharmaceutical compositions are provided which contain hollow fine tube drug delivery systems. The compositions comprise a pharmaceutically suitable carrier, preferably in the form of a capsule, tablet, suspension, or suppository, and at least one drug delivery system which consists essentially of (1) a polymeric tube having a membrane outer sheath and a hollow core, and (2) at least one drug compound contained within the core, said system contained in the composition in an amount sufficient to deliver a therapeutic amount of the drug contained therein at a predetermined rate over a predetermined period of time. By varying the polymer, the permeability of the outer sheath, the drug, the drug concentration in the hollow core of the tube, the tube diameter, the tube length, the tube core diameter, and the sealing of the tube ends, a wide variety of drug therapeutic amounts, rates and dosing times can be achieved.

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