Manufacture of antibiotics

Details Manufacture of antibiotics Manufacture of antibiotics

1984-10-30

1987-05-19

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548194, C07D27740

Patent

active

046670297

ABSTRACT:
The invention provides crystalline (Z)-2-(2-t-butoxycarbonyl-prop-2-oxyimino)-2-(2-triphenylmethylaminothiazo l-4-yl)acetic acid in association with dioxan and its crystalline ethyl ester in association with methanol. The compounds are of value as intermediates in the preparation of .beta.-lactam antibiotics such as ceftazidime or azthreonam.

REFERENCES:
patent: 4166115 (1979-08-01), Takaya et al.
patent: 4258041 (1981-03-01), O'Callaghan et al.
patent: 4288434 (1981-09-01), Heymes
patent: 4294960 (1981-10-01), Takaya et al.
patent: 4493933 (1985-01-01), Brodie

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