Manufacture of antibiotics

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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544 25, C07D27738

Patent

active

045103127

ABSTRACT:
The invention provides crystalline ethyl (Z)-2-hydroxyimino-2-(2-triphenylmethylaminothiazol-4-yl)acetate hydrochloride N,N-dimethylformamide solvate which is of value as an intermediate in the preparation of .beta.-lactam antibiotics such as ceftazidime, azthreonam, cefmenoxime, cefotaxime, ceftriaxon, ceftizoxime and cefodizime.

REFERENCES:
patent: 4098888 (1978-07-01), Ochiai et al.
patent: 4152432 (1979-05-01), Heymes et al.
patent: 4166115 (1979-08-01), Takaya et al.
patent: 4258041 (1981-03-01), O'Callaghan et al.
patent: 4288434 (1981-09-01), Heymes
patent: 4294960 (1981-10-01), Takaya et al.

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