Manufacture of amides

Details Manufacture of amides Manufacture of amides

2004-11-22

2010-10-19

Afremova, Vera (Department: 1657)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing nitrogen-containing organic compound

C435S170000, C435S252200, C435S260000, C435S822000

Reexamination Certificate

active

07816106

ABSTRACT:
A method of producing an amide from the corresponding nitrile comprising the following steps, i) providing a microorganism capable of producing a nitrile hydratase biocatalyst, ii) culturing the microorganism in a growth medium, iii) storing the microorganism, iv) contacting the nitrile by the microorganism in an aqueous medium and thereby converting the nitrile to the amide, wherein the microorganism is stored as none actively growing free cells in a storage medium that comprises water. The stored microorganism may be as whole microbial cells, this may be in the form of a cell paste recovered from a fermentation medium; an aqueous suspension of the microbial cells, prepared using a suitable suspending medium such as water, physiological saline solution, or a suitable buffer solution, such as phosphate or comprises the fermentation broth that contains components of the fermentation culture medium and products of microbial culture. The microorganism exhibits no significant loss of activity, for example if stored even for at least 2 days, especially 3 to 28 days.

REFERENCES:
patent: 4900672 (1990-02-01), Yamada et al.
patent: 4931391 (1990-06-01), Enomoto et al.
patent: 5089411 (1992-02-01), Yamada et al.
patent: 5563053 (1996-10-01), Takashima et al.
patent: 5567608 (1996-10-01), Doi et al.
patent: 5705382 (1998-01-01), Endo et al.
patent: 5827699 (1998-10-01), Yanenko et al.
patent: 5998180 (1999-12-01), Armitage et al.
patent: 6043061 (2000-03-01), Ishii et al.
patent: 6251646 (2001-06-01), Dicosimo et al.
patent: 6368804 (2002-04-01), Ben-Bassat et al.
patent: 6395467 (2002-05-01), Fahy et al.
patent: 2004/0048348 (2004-03-01), Murao et al.
patent: 0 243 966 (1987-11-01), None
patent: 0 307 926 (1989-03-01), None
patent: 2003-144144 (2003-05-01), None
Martinkova et al.; biocatalysis and Biotransformation, vol. 20, No. 2, (2002), pp. 73-93.
Mylerova et al.; Current Organic Chemistry, vol. 7, (9/03), pp. 1279-1295.
Kaufmann et al., Steroids vol. 64 (1999) pp. 535-540.
T. Nagasawa et al.; Appl. Microbiol Biotechnol vol. 34: pp. 783-788 (1991).
T. Nagasawa et al.; Pure & Appl. Chem. vol. 67, No. 7, pp. 1241-1256 (1995).
T. Leonova et al.; Applied Biochemistry and Biotechnology, vol. 88, (2000), pp. 231-241.
A. Yanenko et al., Proceedings of the Ninth Symposium on the Actinomycetes, (1995), pp. 139-144.
T. Nagasawa et al., Eur. J. Biochem. Vol. 196, pp. 581-589 (1991).
Page 47, of Enzyme preparation and use, Chaplin & Bucke (1990), Cambridge University Press.
Patent Abstracts of Japan Pub. No. 2003144144.

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