Drug – bio-affecting and body treating compositions – Dentifrices
Patent
1992-02-21
1993-02-23
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Dentifrices
426534, A61K 716
Patent
active
051888190
ABSTRACT:
An improved method for manufacturing a palatable, aluminum-based anticariogenic composition is described. Critical pH adjustment of aluminum salt solutions is accomplished advantageously by pre-blending the aluminum salt solution with at least a portion of a humectant ingredient component. Cellulosic binder components, when used, are preferably hydrated in the pH-adjusted aluminum/humectant solutions. Consistent product rheology and aluminum availability can be obtained in large-scale preparations by blending the aqueous pH-adjusted aluminum/humectant solution with humectant/surfactant and flavor oil/pH-adjusted surfactant premixes.
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Kleber Carl J.
Putt Mark S.
Purdue Research Foundation
Rose Shep K.
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