Manufacture of a chromatography matrix

Details Manufacture of a chromatography matrix Manufacture of a chromatography matrix

2006-11-16

2009-10-27

Therkorn, Ernest G (Department: 1797)

Liquid purification or separation

Processes

Liquid/liquid solvent or colloidal extraction or diffusing...

C210S656000, C210S198200, C210S502100, C502S404000, C502S439000, C521S033000, C536S124000

Reexamination Certificate

active

07608187

ABSTRACT:
The present invention relates to method of manufacturing a sulphonate-functionalized (S-functionalized) cation exchanger, which method comprises reacting olefinic groups with bisulphite in the presence of at least one amine oxide, such as N-methyl morpholine oxide (NMO). The olefinic groups of the carrier may be allyl groups; which may be provided on extenders such as polyhydroxyfunctional polymers. In one embodiment, the carrier is made of agarose with improved flow pressure properties.

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