Manufacture of 2-amino-1-alcohols

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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260584R, C07D26314, C07C 85145, C07C 8520

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active

041056698

ABSTRACT:
Reaction of 1-hydroxy-2-ketones of the general formula R-- CO-- CH.sub.2 OH, where R is a short alkyl, with ammonia gives a new compound ##STR1## which on hydrogenation gives 2-amino-1-alcohols; the yield can be improved by carrying out the hydrogenation in the presence of ammonia.

REFERENCES:
patent: 4014880 (1977-03-01), Dowd et al.
Frump, "Chemical Reviews", vol. 71, No. 5, pp. 483-505, (1971).

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