Manoalide analogs

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

549313, 549318, A61K 31365, C07D30758

Patent

active

049526057

ABSTRACT:
Analogs of the marine natural product manoalide are useful in treating mammals, including humans, in need of a drug having analgesic/anti-inflammatory, immunosuppressive, and/or antiproliferative activity.

REFERENCES:
patent: 4447445 (1984-05-01), Jacobs et al.
patent: 4616089 (1986-10-01), Jacobs et al.
patent: 4786651 (1988-11-01), Wheeler
patent: 4789749 (1988-12-01), Jacobs et al.
Yunker et al., J. Amer. Chem. Soc. 100: 307-309 (1978).
Bennett et al., Differential Effects of Manoalide on Secreted and Intracellular Phospholipases, Yale University, Dept. of Pharmacology, unpublished.
De Silva et al., Tetrahedron Letters 21: 1611-1614 (1980).
De Silva et al., Tetrahedron Letters 33: 3747-3150 (1981).
Glaser et al., Fed. Proc. 45: 580 (1986).
Glaser et al., Inactivation of Bee Venom Phospholipase A2 by Manoalide, University California, Santa Barbara, unpublished.
Katsumura et al., Heterocycles 10: 87-91 (1978).
Katsumura et al., Tetrahedron Letters 26: 5827-5830.
Kobayashi et al., J. Org. Chem. 45: 5223-5225 (1980).
Larcheveque et al., Tetrahedron Letters 22: 1595-1598 (1981).
Ortiz et al., Tetrahedron Letters 47: 4215-4218 (1976).
Sullivan et al., Tetrahedron Letters 23: 907-910 (1982).
Sum et al., J. Amer. Soc. 101: 4401-4403 (1979).
Sum et al., Tetrahedron 37: 303-317 (1981).
Takahashi Synthetic Communications 6: 331-337 (1976).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Manoalide analogs does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Manoalide analogs, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Manoalide analogs will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1590232

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.