Mannosidase inhibitors, process for their preparation and their

Details Mannosidase inhibitors, process for their preparation and their Mannosidase inhibitors, process for their preparation and their

1995-12-06

1998-06-30

Leary, Louise

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving viable micro-organism

435 15, 435 18, 435 13, 435 4, 435 19, 548530, C12Q 102, C12Q 148, C12Q 134, C12Q 100

Patent

active

057732396

ABSTRACT:
The invention relates to novel mannosidase inhibitors, processes for their preparation and their use as therapeutic agents. The invention also relates to the use of compounds of the formula II as described herein as prodrugs.

REFERENCES:
patent: 4457919 (1984-07-01), Simon et al.
patent: 4837237 (1989-06-01), Rohrschneider et al.
patent: 4839290 (1989-06-01), Kaieda et al.
patent: 4996329 (1991-02-01), Fleet et al.
patent: 5075448 (1991-12-01), Fleet
patent: 5075457 (1991-12-01), Fleet
patent: 5109116 (1992-04-01), Arkwright et al.
patent: 5206356 (1993-04-01), Pierce et al.
patent: 5240707 (1993-08-01), Farr et al.
patent: 5262425 (1993-11-01), Farr et al.
Fuhrmann, E., et al., Nature, 307:755, 1984.
Colegate et al., Aust. J. Chem. 32:2257-2264, 1979.
Molyneux R.J and James L.F., Science 215:190-191, 1981.
Schneider et al., Tetrahedron 39:29-32, 1983.
Tulsiani et al., J. Biol. Chem, 257:7936-7939, 1982.
Fernandes et al., Cancer Res. 51:718-723, 1991.
Dennis J.W., Cell Surface Carbohydrates and Cell Dev., pp. 161-0194. CRC Press, Boca Raton, 1991.
Dennis et al., Science 236:582-585, 1987.
VanderElst I. and Dennis J.W., Exp. Cell Res. 192:612-621, 1991.
Dennis J.W., Cancer Res. 46:5131-5136, 1986.
Humphries et al., Proc. Natl. Acad. Sci. U.S.A. 83:1752-1756, 1986.
Yagel et al., Int. J. Cancer 44:685-690, 1989.
Seftor et al., Melanoma Res. 1:43-54, 1991.
Dennis et al., J. Natl. Cancer Inst. 81:1028-1033, 1989.
Dennis et al., Cancer Res. 50:1867-1872, 1990.
Humphries M.J. and Olden K., Pharmacol Ther. 44:85-105, 1989.
Olden et al., Pharmacol Ther. 50:285-290, 1991.
Humphries et al., Cancer Res. 48:1410-1415, 1988.
Yagita M. and Saksela E., Scand. J. Immunol. 31:275-282, 1990.
White et al., Biochem. Biophys. Res. Commun. 150:615-625, 1988.
Bowlin et al., Cancer Res. 49:4109-41113, 1989.
White et al., Cancer Commun. 3:83-91, 1991.
Oredipe et al., J. Natl. Cancer Institue 83:1149-1156, 1991.
Fleet G.W.J. et al., Chem. Soc. Commun., 1984, 1240-1241.
Palamarczyk et al., Arch. Biochem. Biophys. 243:35-45, 1985.
Fleet et. al., FEBS Lett. 237:128-132, 1988.
Fleet et al., Tetrahedron 44:2649-2655, 1988. (Abstract).
Hino et al., J. Antibiotics, 38(7):926-935, 1985.

Affiliated with

Also associated with

Rating

Mannosidase inhibitors, process for their preparation and their does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Mannosidase inhibitors, process for their preparation and their , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mannosidase inhibitors, process for their preparation and their will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1857727