Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Binds antigen or epitope whose amino acid sequence is...
Reexamination Certificate
2002-11-21
2009-11-17
Belyavskyi, Michail A (Department: 1644)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Binds antigen or epitope whose amino acid sequence is...
C424S141100, C530S387100, C530S388100
Reexamination Certificate
active
07618629
ABSTRACT:
The invention provides methods for modulating cytokine levels, GM-CSF levels and the immune system using CD83 nucleic acids, CD83 polypeptides, anti-CD83 antibodies and factors that influence CD83 activity or expression. The invention also provides mice having a mutant CD83 gene and mice having a transgenic CD83 gene, which are useful for defining the role of CD83 in the immune system and for identifying compounds that can modulate CD83 and the immune system.
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Appleby Mark W.
Garcia-Martinez Leon Fernando
Proll Sean C.
Ramsdell Fred
Staehling-Hampton Karen
Belyavskyi Michail A
Celltech R&D, Inc.
K&L Gates LLP
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