Manifold vacuum device for biochemical and immunological uses

Details Manifold vacuum device for biochemical and immunological uses Manifold vacuum device for biochemical and immunological uses

1987-03-19

1988-10-11

Scott, Samuel

Chemical apparatus and process disinfecting, deodorizing, preser

Control element responsive to a sensed operating condition

435301, 436178, B01L 1100

Patent

active

047770210

ABSTRACT:
A device for simultaneously performing multiple biochemical or immunological reactions. A manifold plate rests atop a waste fluid collection chamber or receptacle suitable for attachment to a vacuum pump. The manifold contains a series of wells that serve as reaction vessels. The sides of each well are fluid-impermeable, and its lower end provides a planar, annular base. A hydrophobic membrane is sealed to the lower surface of the base of each well. The membrane is formed of a material through which fluid can be drawn upon application of vacuum while retaining the fluid within the well in the absence of vacuum. By placement of a solid-phase support for binding biological coreactants atop the membrane prior to initiation of the reaction, solid-phase reaction products can be collected when vacuum is applied and can then be freely withdrawn from its well. The membranes of all of the reaction wells are physically isolated from each other so that totally independent biochemical or immunological reactions can be performed in each well without danger of cross-contamination between wells.

REFERENCES:
patent: 4246339 (1981-01-01), Cole et al.
patent: 4407943 (1983-10-01), Cole et al.
patent: 4427415 (1984-01-01), Cleveland
patent: 4493815 (1985-01-01), Fernwood et al.
patent: 4526690 (1985-07-01), Kiovsky et al.
patent: 4642220 (1987-02-01), Bjorkman
patent: 4645602 (1987-02-01), Barnes, Jr. et al.
patent: 4704255 (1987-11-01), Jolley

Affiliated with

Also associated with

Rating

Manifold vacuum device for biochemical and immunological uses does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Manifold vacuum device for biochemical and immunological uses, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Manifold vacuum device for biochemical and immunological uses will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1957365