Mammalion cell culture process

Details Mammalion cell culture process Mammalion cell culture process

1976-04-12

1978-05-02

Tanenholtz, Alvin E.

Textiles: fiber preparation

195127, C12K 900, C12B 110

Patent

active

040873277

ABSTRACT:
A cell culture reactor system is provided for the growth of cells in vitro which employs elongate hollow or solid fibers arranged in a shallow layer configuration as a matrix for cell attachment in which the flow path of the culture media is directed substantially uniformly through the fiber layer and substantially transverse to the plane of the elongate axes of the fibers.

REFERENCES:
patent: 3342729 (1967-09-01), Strand
patent: 3746175 (1973-07-01), Markley
patent: 3821087 (1974-06-01), Knazek et al.
patent: 3843454 (1974-10-01), Weiss
patent: 3883393 (1975-05-01), Knazek et al.
patent: 3997396 (1976-12-01), Delente
Schratter, "Synthetic Capillaries for Cell Culture," American Laboratory, vol. 6, No. 10 (Oct. 1974), pp. 33-38.
Bulletin of Amicon Corporation, 1975, "Membrane Perfusion by Artificial Capillaries."
Williams et al, "A Hollow Filament Fabric Blood Oxygenator", Proceedings Artificial Heart Program Conference, NIH, Bethesda, (1969), pp. 365-371.

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