Mammalian telomerase

Details Mammalian telomerase Mammalian telomerase

1995-06-07

1999-09-28

Degen, Nancy

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

4353201, 435366, 536 241, 536 245, 536 251, 536 252, C12Q 168, C12N 508, C12N 1563, C07H 2102

Patent

active

059586800

ABSTRACT:
Nucleic acids comprising the RNA component of a mammalian telomerase are useful as pharmaceutical, therapeutic, and diagnostic reagents.

REFERENCES:
patent: 5489508 (1996-02-01), West et al.
patent: 5643890 (1997-07-01), Iversen et al.
Kim et al. (1994), Specific Association of Human Telomerase Activity with Immortal Cells and Cancer, Science 266:2011-2014.
Pestka et al. Antisense RNA, History and perspective. Ann. N.Y. Acad. Sci. vol. 660:251-262, Feb. 4, 1993.
Xiao et al. Adeno-asociated virus (AAV) vectors for gene transfer. Adv. Drug Del. Rev. vol. 12:201-215, Feb. 1993.
Chatterjee et al. Dual-target inhibition of HIV-1 in vitro by means of an adeno-associated virus antisense vector. Science. vol. 258:1485-1488, Nov. 27, 1992.
Dahse et al. Telomeres and telomerase: biological and clinical importance. Clin. Chem. vol. 43(5):708-714, May 13, 1997.
Marshall. Gene therapy's growing pains. Science vol. 269:1050-1055, Aug. 25, 1995.

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