Mammalian putative phosphatidylinositol-4-phosphate-5-kinase

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease

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4353201, 435325, 4352523, 435 6, 536 232, 536 2431, C12N 912, C12N 120, C12N 1500, C12Q 168, C07H 2104

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active

061107182

ABSTRACT:
A novel mammalian phosphatidylinositol-4-phosphate-5-kinase (PIP5K) referred to herein as p235 and novel polynucleotides encoding p235, are provided. p235 is specifically expressed in adipocytes and myocytes and is believed to be involved in insulin-induced membrane trafficking. Therapeutic, diagnostic and research methods utilizing the novel polynucleotides and proteins are also provided.

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