Mammalian model of a malignant disorder

Details Mammalian model of a malignant disorder Mammalian model of a malignant disorder

1994-05-12

1997-11-04

Chambers, Jasemine C.

Multicellular living organisms and unmodified parts thereof and

Nonhuman animal

800DIG5, 424 92, 424 937, 424573, A61K 4800, A61K 4900

Patent

active

056842210

ABSTRACT:
A method for producing a mouse having a systemic malignant disease which mimics a human IL-2 expressing. T-cell malignancy, which includes administering to a mouse a mixture of passaged cells comprising cancer causing cells, the mixture having been rendered cancer causing by in vivo passage of tumor inducing cells in athymic mice.

REFERENCES:
Gillis et al., Nature, vol. 268, Issued Jul. 14, 1977, pp. 154-156.
Linden et al., BR. J. Cancer, vol. 58, Issued 1988, pp. 614-618.
Russell et al., Int. J. Cancer, vol. 44, Issued 1989, pp. 276-285.
Brunson et al., J. Nat'l. Cancer Inst. 61:1499, 1978.
Avent et al., J. Surgical Oncology 12:87, 1979.
Schirrmacher et al., Int'l. J. Cancer 23:233, 1979.
Miner et al., Cancer Res. 43:2063, 1983.
Brinster et al., Cell 37:367, 1984.
Steward et al., Cell 38:627, 1984.
Adams et al., Nature 318:533, 1985.
Diamantstein et al., Brit. J. Cancer 51:23, 1985.
Ruggiero et al., Brit. J. Cancer 51:37, 1985.
Hanahan et al., Nature 315:115, 1986.
Yamada et al., EMBO J. 6:2705, 1987.
Muller et al., Cell 54:105, 1988.
Hariharan et al., Mol. Cell. Biol. 9:2798, 1989.
Kiyokawa et al., Cancer Res. 49:4042, 1989.
Samid et al., Clinical Biotech. 1:21, 1989.
Lugasi et al., Int'l. J. Cancer 45:163, 1990.
Bacha et al., J. Exp. Med. 167:612-622 (1988).

Affiliated with

Also associated with

Rating

Mammalian model of a malignant disorder does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Mammalian model of a malignant disorder, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mammalian model of a malignant disorder will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1834661