Mammalian MDM2 binding proteins and uses thereof

Details Mammalian MDM2 binding proteins and uses thereof Mammalian MDM2 binding proteins and uses thereof

2007-01-23

2007-01-23

Nashed, Nashaat T. (Department: 1656)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S252300, C435S320100, C530S358000

Reexamination Certificate

active

10312954

ABSTRACT:
Isolated nucleic acid sequences encoding mammalian MDM2 binding protein and polypeptide sequences for the mammalian MDM2 binding protein are provided. Also provided are vectors containing these nucleic acid sequences, host cells which express these proteins and antibodies targeted to these proteins. In addition, methods and compositions for modulating the G1phase of the cell cycle via altering expression and/or activity of a mammalian MDM2 binding protein are provided.

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