Chemistry: molecular biology and microbiology – Spore forming or isolating process
Patent
1993-08-06
1996-02-20
Walsh, Stephen G.
Chemistry: molecular biology and microbiology
Spore forming or isolating process
43525231, 43525411, 4353201, 435 691, 536 235, C12N 1512, C12N 1563, C12N 510, C12N 121
Patent
active
054928257
ABSTRACT:
This disclosure relates to two separate and distinct inward rectifier K.sup.+ channel expression products and the the genes which encode each expression product. The IRK1 gene (SEQ. ID NO: 1) encodes an inward rectifier K.sup.+ channel and the GIRK1 gene (SEQ. ID NO: 31) encodes a G protein coupled muscarinic K.sup.+ channel. The disclosure relates to the uses of these expression products, particularly in combination with identifying physiological processes mediated by these channels, such as regulation of heartbeat and insulin release and materials modulating or blocking same.
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Jan Lily Y.
Jan Yuh N.
Kubo Yoshihiro
Brunelle Jan P.
Dreger Walter H.
Fitzgerald David L.
The Regents of the University of California
Walsh Stephen G.
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