Mammalian interleukin-4

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435 6952, 435 712, 435 91, 4351723, 4352402, 43525233, 424 852, 935 18, 935 29, 935 32, 935 41, 935 56, 935 58, 935 62, 935 70, 935 73, 935 81, C12N 1500, C12N 500, C12N 122, A61K 3900, C07K 1300, C12P 1206, C12P 2104, C12P 1934

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050176919

ABSTRACT:
Mammalian proteins and muteins thereof, designated interleukin-4s (IL-4s), are provided which exhibit both B cell growth factor activity and T cell growth factor activity. Compounds of the invention include native human and murine IL-4s, muteins thereof, and nucleic acids which are effectively homologous to disclosed cDNAs, and/or which are capable of coding for mammalian IL-4s and their muteins.

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