Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-12-22
2000-12-05
Schwartzman, Robert A.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
536 235, C12N 1512, C12P 2100
Patent
active
061565350
ABSTRACT:
Disclosed is substantially pure DNA encoding mammalian IAP polypeptides; substantially pure polypeptides; and methods of using such DNA to express the IAP polypeptides in cells and animals to inhibit apoptosis. Also disclosed are conserved regions characteristic of the IAP family and primers and probes for the identification and isolation of additional IAP genes. In addition, methods for treating diseases and disorders involving apoptosis are provided.
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Baird Stephen
Korneluk Robert G.
Liston Peter
MacKenzie Alexander E.
Brady Kristina Bieker
Schwartzman Robert A.
University of Ottawa
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