Mammalian IAP gene family, primers, probes and detection...

Details Mammalian IAP gene family, primers, probes and detection... Mammalian IAP gene family, primers, probes and detection...

2006-06-27

2006-06-27

Kaushal, Sumesh (Department: 1633)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S320100, C435S325000, C435S455000, C530S300000, C530S350000, C530S351000, C536S023100, C536S023500

Reexamination Certificate

active

07067281

ABSTRACT:
Disclosed is substantially pure DNA encoding mammalian IAP polypeptides; substantially pure polypeptides; and methods of using such DNA to express the IAP polypeptides in cells and animals to inhibit apoptosis. Also disclosed are conserved regions characteristic of the IAP family and primers and probes for the identification and isolation of additional IAP genes. In addition, methods for treating diseases and disorders involving apoptosis are provided.

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