Mammalian host cell modified by RNAi to inhibit α...

Details Mammalian host cell modified by RNAi to inhibit α... Mammalian host cell modified by RNAi to inhibit α...

2008-07-01

2008-07-01

Woitach, Joseph (Department: 1633)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

C435S375000, C435S232000, C435S007800, C435S070100, C800S008000

Reexamination Certificate

active

11287324

ABSTRACT:
The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.

REFERENCES:
patent: 5728568 (1998-03-01), Sullivan et al.
patent: 6054304 (2000-04-01), Taniguchi
patent: 1 176 195 (2002-01-01), None
patent: 97/27303 (1997-07-01), None
patent: WO97/30087 (1997-08-01), None
patent: 97/37683 (1997-10-01), None
patent: 99/54342 (1999-10-01), None
patent: 99/64618 (1999-12-01), None
patent: 00/61739 (2000-10-01), None
Hunter (1999) Current Biology, 9: R440-42.
Shinoda, et al. (1998) Glycoconjugate Journal, 15: 1079-83.
Staudacher (1999) Biochimica et Biophysica Acta, 1473: 216-236.
Shitara et al. Journal of Immunological Methods,167, 271-278 (1994).
Furukawa et al Protein, Nucleic Acid and Enzyme,43, 2309-2317 (1998).
Oriol et al, Glycobiology, 9, No. 4, 323-334 (1999).
Breton et al, Glycobiology, 8, No. 1, 87-94 (1998).
Asano et al, The EMBO Journal, vol. 16, No. 8, pp. 1850-1857 (1997).
Maly et al, Cell , vol. 86, 643-653, Aug. 23, 1996.
Wright et al. Tibtech, 15, 26-32 (1997).
Raju, et al. (2000) Glycobiology, 10(5): 477-86.
Stryer (1988) Biochemistry, 3rdEd., Freeman and Co., New York, NY, pp. 35-37.
Shinkawa, et al. (2003) J. Biol. Chem., 278(5):3466-73.
Jones, et al. (2001) Pharmacogenomics J., 1(2): 126-34.
Lifely, et al. (1995) Glycobiology, 5(8): 813-22.
Ripka et al, Archives of Biochemistry and Biophysics, 1986, vol. 249, No. 2, pp. 533-545.
Ohyama et al, The Journal of Biological Chemistry, 1998, vol. 273, No. 23, pp. 14582-14587.
Wang et al, The Journal of Biological Chemistry, 1998, vol. 273, No. 14, pp. 8112-8118.
Umana et al, Nature Biotechnology, 1999, vol. 17, pp. 176-180.
Supplementary European Search Report dated Jun. 1, 2005 issued in connection with EP 01974718.7.
Canadian Office Action dated Jul. 31, 2007, issued in connection with Canadian Application No. 2,424,602.
Accession No. NM 016893, NCBI (Jul. 4, 2007), Hayashi et al, DNA Seq. 11 (1-2), 91-96 (2000).
Accession No. NP 058589, NCBI (Jul. 4, 2007), Hayashi et al, DNA Seq. 11 (1-2), 91-96 (2000).
Hayashi et al, “Molecular Cloning of Mouse Alpha-1,6-Fucosyltransferase and Expression of Its mRNA in the Developing Cerebrum”, DNA Sequence, 2000, vol. 11(1-2), pp. 91-96.

Affiliated with

Also associated with

Rating

Mammalian host cell modified by RNAi to inhibit α... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Mammalian host cell modified by RNAi to inhibit α..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mammalian host cell modified by RNAi to inhibit α... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3912353