Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.
Reexamination Certificate
2007-02-27
2007-02-27
Chan, Christina (Department: 1644)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Lymphokines, e.g., interferons, interlukins, etc.
C530S827000, C536S023400, C536S023500, C435S320100, C435S325000, C435S069700, C435S070100
Reexamination Certificate
active
10375706
ABSTRACT:
Purified genes encoding cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using said reagents and diagnostic kits are also provided.
REFERENCES:
patent: 5547852 (1996-08-01), Seiler et al.
patent: 5571515 (1996-11-01), Scott et al.
patent: 5650492 (1997-07-01), Gately et al.
patent: 5744132 (1998-04-01), Warne et al.
patent: 5853721 (1998-12-01), Gately et al.
patent: 5891680 (1999-04-01), Lieschke et al.
patent: WO 99/05280 (1999-02-01), None
The American Heritage College Dictionary, Third Edition. [1993] definition of “surmise.” Houghton Mifflin Company, Boston. p. 1366.
A.M. Ackrill,Genbank, Accession No. X97019, Apr. 11, 1996. “M.monax mRNA for II-12 p40 subunit.”
G.F. Belke-Louis and M. Buettner, et al.,Genbank, Accession No. U49100, Mar. 13, 1996. “Canis familiaris interleukin-12 p40 subunit mRNA, complete cds.”
J.C. Beyer, et al.,Genbank, Accession No. AF007576, Jul. 14, 1997. Capra hircus interleukin 12 p40 subunit (IL-12) mRNA, complete cds.
D. Fehr, et al.,Genbank, Accession No. U83184, Jul. 16, 1999. “Felis catus interleukin-12 p40 subunit (IL-12) mRNA, complete cds.”
M. Fischer, et al.,Nature Biotechnology, 15: 142-145, 1997. “A bioactive designer cytokine for human hematopoietic progenitor cell expansion”.
M.K. Gately, et al.,Annual Review of Immunology, 16:495-521, 1998. “The interleukin-12 /interleukin-12-receptor syste m: role in normal and pathologic immune responses”.
R.E. Goodman and G.B. Toews,GenBank, Accession No. U16674, Nov. 7, 1994, “Rattus norvegicus interleukin-12p40 mRNA, partial cds.”
Angela Gronenborn and G.M. Clore,Protein Engineering, 4(3):263-269, 1991. “Modeling the three-dimensional structure of the monocyte chemo-attractant protein MCAF/MCP-1 on the basis of the solution structure of interleukin-8”.
J. Grotzinger, et al.,Proteins, 27:96-109, 1997. “The family of the IL-6-type cytokines: specificity and promiscuity of the receptor complexes”.
U. Gubler, et al.,Genbank, Accession No. M65272, Apr. 27, 1993. “Human cytotoxic lymphocyte maturation factor 40 kDa subunit mRNA, complete cds.”
J. Khalife, et al.GenBank, Accession No. AF133197, Apr. 8, 1999. “Rattus norvegicus interleukin-12 p40 precursor, mRNA, complete cds.”
T. Kitamura, et al.,Proceedings of the National Academy of Sciences, USA, 92:9146-9150, 1995. “Efficient screening of retroviral cDNA expression libraries”.
E. Lockhart, et al.,Genbank, Accession No. U57752, Oct. 28, 1999. “Cervus elaphus interleukin-12 p40 subunit mRNA, complete cds.”
L. Nicolson, et al.,Genbank, Accession No. Y11129, Nov. 17, 1999. “Equus caballus mRNA for interleukin 12 p40 subunit.”
M. Onishi, et al.,Experimental Hematology, 24:324-329, 1996. “Applications of retrovirus-mediated expression cloning”.
M. Onishi, et al.,Blood, 88: 1399-1406, 1996. “Identification of an oncogenic form of the thrombopoietin receptor MPL using retrovirus-mediated gene transfer”.
Malte Peters, et al.,The Journal of Immunology, 161:3575-3581, 1998. “In Vivo and In Vitro Activities of the gp130-Stimulating Designer Cytokine Hyper-IL-6”.
Douglas Presky, et al.,Proceedings of the National Academy of Sciences, USA, 93:14002-14007, Nov. 1996 “A functional interleukin 12 receptor complex is composed of two Beta-type cytoline receptor subunits”.
Tim Rakemann, et al.,The Journal of Biological Chemistry, 274:1257-1266, 1999. “The Designer Cytokine Hyper-Interleukin-6 Is a Potent Activator of STAT3-dependent Gene Transcriptionin Vivoandin Vitro”.
Roger Sayle and E.J. Milner-White,Trends in Biochemical Sciences, 20:374-376, 1995. “RASMOL: biomolecular graphics for all”.
V.E. Schijns, et al.,Genbank, Accession No. Y07762, May 13, 1997. “F.catus mRNA for interleukin-12 p40 chain.”
D.S. Schoenhaut, et al.,GenBank, Accession No. M86671, May 8, 1993. Definition: “Mus musculus interleukin 12 p40 subunit, complete cds.”
S.J. Swinburne, et al.,Genbank, Accession No. AF004024, Nov. 14, 1999. “Ovis aries interleukin-12 p40 subunit precursor, mRNA, complete cds.”
T. Taga and T. Kishimoto,Annual Review of Immunology, 15: 797-819, 1997. “Interleukin-12: a cytokine at the surface of inflammation and immunity”.
G. Trinchieri,Advances in Immunology, 70:83-243, 1998. “Interleukin-12: a cytokine at the interface ofinflammation and immunity”.
G. Trinchieri,Int. Rev. Immunol., 16:365-396, 1998. “Proinflammatory and Immunoregulatory Functions of Interleukin-12”.
T. Tsukamoto, et al.,Biochemicist and Biophysicist Research Community, 265: 7-12, 1999. “Isolation of oncogenes from rat mammafy tumors by a highly efficient retrovirus expression cloning system”.
F. Villinger, et al.,Genbank, Accession No. U19834, Feb. 3, 1996. “Cercocebus torquatus interleukin-12 alpha p40 subunit (IL-12a) mRNA, complete cds.”
F. Villinger, et al.,Genbank, Accession No. U19841, Feb. 3, 1996. “Macaca mulatta interleukin-12 alpha (IL-12a) mRNA, complete cds.”
Chang-You Wu, et al.European Journal of Immunology, 26:345-350, 1996. “Biological function and distribution of human interleukin-12 receptor chain Beta”.
D.S. Zarlenga, et al.,Genbank, Accession No. U11815, Feb. 27, 1996. “Bos taurus interleukin 12 40 kDa subunit mRNA, complete cds.”
De Waal Malefyt Rene
Kastelein Robert A.
Lira Sergio A.
Narula Satwant K.
Oppmann Birgit
Chan Christina
Ching Edwin P.
Hwung Ping F.
McKeon Tina W.
Schering Corporation
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