Mammalian expression of the bone morphogenetic protein-2B using

Details Mammalian expression of the bone morphogenetic protein-2B using Mammalian expression of the bone morphogenetic protein-2B using

1990-05-24

1992-12-01

Lacey, David L.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

536 27, 435240, 4353261, 530350, C12P 2106, C12P 1934, C12N 1500, C12N 700, C12N 500, C12N 122, C12N 116

Patent

active

051680505

ABSTRACT:
A DNA construct is provided comprising DNA encoding a mature BMP-2 upstream of which is DNA encoding a precursor portion of a mammalian protein other than the BMP-2. Also provided are mammalian expression vectors and hosts containing such a DNA construct and methods for improved expression using such construct.

REFERENCES:
patent: 4877864 (1989-10-01), Wang et al.
patent: 5013649 (1991-05-01), Wang et al.
Hammonds et al., Mol. Endocr., 5(1):149-155 (1991).
Dayhoff et al., Meth. in Enzymol., 91:524-545 (1983).
Plessow et al., Biochem. Biophys. Acta, 1089:280-282 (1991).
Koster et al., Mech. Dev., 33:191-200 (1991).
Wozney et al., Science, 242:1528-1534 (1988).
Roberts & Sporn, Handbook of Experimental Pharmacology, Peptide Growth Factors and Their Receptors I, Sporn and Roberts, eds., (Springer-Verlag: Berlin, 1990) pp. 419-472.
Wakefield et al., J. Biol. Chem., 263(16):7646-7654 (1988).
Wakefield et al., Growth Factors, 1:203-218 (1989).
Gray and Mason, Science, 247:1328-1330 (1990).
Brunner et al., J. Biol. Chem., 264(23):13660-13664 (1989).
Wang et al., PNAS USA, 87:2220-2224 (1990).

Affiliated with

Also associated with

Rating

Mammalian expression of the bone morphogenetic protein-2B using does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Mammalian expression of the bone morphogenetic protein-2B using , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mammalian expression of the bone morphogenetic protein-2B using will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-503350