Mammalian collagenase inhibitors

Details Mammalian collagenase inhibitors Mammalian collagenase inhibitors

1981-10-07

1983-02-22

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424177, C07C10352, A61K 3700

Patent

active

043747655

ABSTRACT:
The polypeptides R-Gly-L-Cys-Gly-L-Glu-L-Glu-NH.sub.2 or a pharmaceutically acceptable salt thereof act as collagenase inhibitors useful in the treatment of disease involving excessive tissue destruction by collagenase.

REFERENCES:
patent: 4235885 (1980-11-01), Sundoon et al.
patent: 4276284 (1981-06-01), Brown
Ajinomoto, K. K., "Japanese Patent Abstract", 3028-165, 8-30-76.
Harper, "Ann. Rev. Biochem.", 1980, 49:1663-1078.

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