Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease
Reissue Patent
2002-10-09
2009-06-23
Sisson, Bradley L (Department: 1634)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Transferase other than ribonuclease
C435S193000, C530S324000, C530S326000, C530S350000
Reissue Patent
active
RE040789
ABSTRACT:
The present invention relates to the isolation of gene sequences encoding mammalian cell cycle checkpoints, as well as the expression of the encoded proteins using recombinant DNA technology. The expressed proteins are used to generate specific antibodies and to inhibit the growth of cells. The human checkpoint gene sequences are used as a probe for a portion of the chromosome associated with tumors and other malignancies, as well as growth and/or development deficiencies.
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Elledge Stephen J.
Sanchez Yolanda
Baylor College of Medicine
Molen Monique Vander
Sewell Gardere Wynne
Sickler Jennifer S.
Sisson Bradley L
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