Mammalian cancer cell and transgenic mammal carrying human...

Details Mammalian cancer cell and transgenic mammal carrying human... Mammalian cancer cell and transgenic mammal carrying human...

2001-07-11

2008-12-02

Li, Q. Janice (Department: 1633)

Multicellular living organisms and unmodified parts thereof and

Nonhuman animal

Transgenic nonhuman animal

C800S008000, C800S009000, C800S010000, C800S013000, C424S093200, C424S093210

Reexamination Certificate

active

07459602

ABSTRACT:
The present invention provides a mammalian cell transfected with an expression vector comprising a human protooncogene which has the nucleotide sequence of SEQ ID NO: 1; a mammalian embryo carrying a nucleic acid construct comprising the human protooncogene; a transgenic cancer mammal, which is derived from the mammalian embryo; and a kit for diagnosing a cancer selected from the group consisting of breast, kidney, ovary and stomach cancers, which comprises a probe having the nucleotide sequence complementary to mRNA transcribed from the human protooncogene or a portion of the mRNA; or an antibody binding specifically to a protein translated from the mRNA or a portion of the protein.

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